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KMID : 0380319920490000161
Journal of Korean Research Institute for Better Living
1992 Volume.49 No. 0 p.161 ~ p.176
The Effect of Ginseng Root on the Distribution of Cerebral Nerve Cells and Circulatory System in Carbon Monoxide Intoxicated Animals


Abstract
The purpose of this study is to investigate the changes of the distribution of nerve cells and circulatory system induced by carbon monoxide intoxication and the effect of ginseng root on this changes.
Carbon monoxide exposure reduced the number of nerve cells in cerebral cortex of mice and ginseng saponins ameliorated the reduction of the number of nerve cells. Blood pressure changes induced by chronic carbon monoxide exposure were measured for 6 weeks. Blood pressure was decreased by carbon monoxide intoxication for 2 weeks and returned to the control level after 2 weeks. Measurement of hemoglobin concentration, hematocrit and heart weight were performed on rats exposed to hypoxia induced by carbon monoxide. Hemoglobin concentration, hematocrit and heart weight were increased significantly by carbon monoxide exposure. Blood pressure decrease of CO exposured rats lasted by administration of ginseng water extracts. Homoglobin concentration, hematocrit and heart weight were not affected by ginseng water extracts.
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